An annual course ran in the Department of Medical Microbiology Laboratories

Curriculum organizer: Dr David P. Kateete (This email address is being protected from spambots. You need JavaScript enabled to view it. )
Course coordinator (2010): Francis Mumbowa and Geraldine Nalwadda
Office Location: Department of Medical Microbiology, 2nd floor Pathology/Microbiology BLDG, Upper Mulago hill road, Kampala, Uganda
Office Phone +256 414 541830
Office Fax: + 256 414 533033
Website: www.mbl.mak.ac.ug; Email address: This email address is being protected from spambots. You need JavaScript enabled to view it.
Office hours: 8.00 am – 5.00 pm                        
Preamble

Immunology and molecular techniques, originally developed in research settings, have been commercially packaged into a myriad of formats that are sufficiently quick and simple for effective use in clinical diagnosis and control of infectious diseases and non-infectious diseases. Currently, there is an emphasis on diagnosis and epidemiology of infectious diseases utilizing molecular and immunological/serological methods. In developing countries, clinicians and health workers in general need to be aware of the tremendous power of these novel tests in the control of common infectious diseases. The use of these procedures transcends health/science, and is now common practices in legal proceedings, where lawyers and politicians come face to face with molecular biology/immunology. Furthermore, the use of these tests is rapidly extending to clinical settings in Africa, especially major referral hospitals. Thus, there is a need for clinicians, health workers, lawyers and politicians to be trained in the theory and practice of performing of molecular or immunological tests. Clinicians, scientists, technologists, and technicians in low income settings must be adept with molecular biology and immunology so as to help in interpreting, developing and improving these tests in individual settings.

Thus, the goal of this course is to introduce applicants particularly those in the health sector to modern methods used in the diagnosis and control of infectious diseases. Where necessary, the techniques will be as well extended to non infectious diseases and conditions.
Up to 20 applicants will be selected.

When?
The course will be run annually in summer (July/August) of every year. However, applications are accepted throughout the year but the course will strictly run in July/August of every calendar year. Applications received after August will be carried forward to the proceeding year.
International applicants are particularly welcome.

Duration
Under relaxed circumstances, the course can be run for a maximum of eight (8) weeks; however, we will endeavor to condense the materials into one month (unless otherwise requested by applicants to extend it over eight weeks).

Who should apply?

  • Undergraduate students with a keen interest in molecular biology or those preparing for a future career in research or academics.
  • Graduate students who wish to acquire specialized skills in molecular diagnostics, molecular epidemiology and diagnostic immunology, which is relevant for their graduate research dissertations.
  • Health care workers (clinicians/doctors, nurses, pharmacists) who wish to acquire knowledge in the emerging themes in molecular diagnostics/molecular epidemiology
  • Veterinary surgeons/scientists
  • Research Scientists
  • Medical laboratory technologists/technicians 
  • Lawyers and policy makers

NOTE: A beginners course for high school students (O’ and A’ levels) with a keen interest in molecular biology or those preparing for a scientific career will be ran in January. Course fees, rules and regulations are the same.

Course fees:

  • $750 (Ugandans)
  • $1000 (international applicants)

The course fee caters for only administrative and laboratory costs. Accommodation and living expenses will be met by the individual applicants. Accommodation exists at Mulago hospital guest house at $25 per night (bed and breakfast). Please book early (Tel: 256-772-345054 or 256-414-541830) in case you intend to stay at the guest house as reservations fill up quickly.

Course aims

Applied & Diagnostic molecular biology/Immunology introduces participants to the advances in immunology and molecular genetics in the diagnosis, control and understanding of infectious diseases. The course describes the principles of immunology and Molecular Biology and how these are exploited for the treatment, diagnosis and/or control of common infections in the tropics. The technology, theory and practical approaches of common immunological/molecular genetics methods to the pathogenesis, diagnosis and understanding of infectious diseases is explained and demonstrated practically.

We primarily focus on how the methods are employed in the fields of Diagnostics, microbial drug resistance and epidemiology in the control of major diseases in the tropics: Tuberculosis (TB), HIV/AIDS, Malaria and Sepsis pathogens etc.

The following courses are emphasized:

Molecular diagnostics: The theory and practice of molecular techniques currently used in the diagnosis/detection of microbial pathogens is taught. The session also extends to non-communicable diseases such as cancers and other diseases.

Microbial drug resistance: The principles and current molecular techniques used for the detection of microbial drug resistance are taught.

Molecular epidemiology: The principle and current molecular techniques used in disease surveillance and microbial typing are taught. Emphasis is on tuberculosis, HIV/AIDS and infections due to sepsis pathogens.

Diagnostic immunology: The current serological and immunological techniques used in th diagnosis of microbial pathogens and a few non-infectious diseases are taught. Emphasis is on the algorithms for developing countries, particularly for HIV/AIDS, TB, Malaria and Syphilis.

Learning Outcomes

By the end of the course, you will be able to:

  • To have understood the concepts and applications of Good clinical laboratory practices (GCLP)
  • To explain the scope of molecular biology and immunology in the view of diagnostics and disease control
  • Describe specimen collection, transportation, processing and storage in the view of molecular diagnostics and diagnostic immunology
  • Describe the immunological and molecular diagnostic tests that can be used to diagnose/detect and the common microbial diseases
  • List the major clinical/medical uses of immunological and molecular diagnostic techniques
  • Able to classify the various commercial immunological and molecular diagnostic techniques
  • Able to discuss clinical applications of immunological and molecular diagnostic techniques
  • Able to discuss genetic methods currently used in predicting drug resistance, transmission patterns, and evolutionary trends in infectious diseases of public health importance
  • Describe the acceptable workflow and proper design of immunology and molecular diagnostic laboratories

Course instructors (2010)

Prof. Moses Joloba, MBChB, MS, PhD
Professor of medicine (infectious diseases/mycobacteriology/GCLP) and molecular medicine;
Head, department of Medical Microbiology, School of \biomedical Sciences,
Makerere University college of Health Sciences

Interests: pathogen biology aiming at discovery of drug targets/vaccine candidates; Policy; GCLP; infectious diseases (tuberculosis) microbial typing; mentoring graduate students into high caliber independent researchers 
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Dr. David P Kateete, B.Vet.Med, MSC, Doctoral student
Lecturer, Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences,

Interests: pathogen biology aiming at discovery of drug targets/vaccine candidates; molecular diagnostics; microbial typing; bioinformatics/Omics
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Dr. Eddie Wampande, B.Vet.Med, MSC, Doctoral student                                                
Lecturer, Department of Veterinary Medicine
Fuculty of Veterinary Medicine
Makerere University

Interests: Molecular parasitology; molecular epidemiology (mycobacteria); Proteins  
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Dr. Freddie Bwanga, MBChB, MMed, PhD
Lecturer, Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Infection Biology; molecular mechanisms of microbial drug resistance; health systems research; MDR Tuberculosis; Forensic medicine
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

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Dr. Benon Asiimwe, B.Vet.Med., MSC, PhD
Lecturer, Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Molecular epidemiology; infectious diseases research; microbial typing   (mycobacteria); zoonotic pathogens
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Dr. Henry Kajumbula, MBChB, MMED
Senior lecturer, Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: virology; infectious diseases research; laboratory medicine
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Dr. Steve Cose, PhD
Honorary lecturer, Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Immunobiology
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Dr Hakim Sendagire, MBChB, MSc, PhD
Lecturer, Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Molecular Parasitology; anti-retroviral research; Malaria 
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Dr. Misaki Wayengera, MBChB
Lecturer, Dept of Pathology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Bioinformatics/functional genomics
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Dr. Sam Nsobya, BBLT, MSC, PhD
Dept of Medicine,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Molecular Parasitology; anti-retroviral research; Drug resistance
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Mr. William Ssengooba, BBLT
Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Tuberculosis; health systems research; GCLP
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Mr Fred Katabazi, BBLT
Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Molecular epidemiology; infectious diseases research; microbial typing   (mycobacteria)
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
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Mr. Okee Moses, BBLT
Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Infectious diseases research; microbial typing
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Mr. Samuel Kirimunda
Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: molecular microbiology; diagnostic immunology
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Mr. Alfred Okeng
Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Molecular mechanisms of microbial drug resistance; health systems research; MDR Tuberculosis;
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Mr. Francis Mumbowa
Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: TB Culture systems; mycobacteriology
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
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Mr. David Martin K Ssemambo
Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Hematology; TB immunology
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Mr. Odongo Paul
Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
           
Interests: Diagnostic immunology; molecular diagnostics

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
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Course Administrators

Geraldine Nalwadda
Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences
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Joan Basemera  
Dept of Medical Microbiology,
School of biomedical Sciences,
Makerere University college of Health Sciences        
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
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Pioneer students and alumni for 2010 practicum

  • Dr. Florence Mutua, MBChB, MSc., University of Nairobi

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  • Kanwagi Micheal, BPharm, Makerere University College of Health Sciences

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  • Tusabe Harrison, Dip MLT, Mulago & Mabarara hospitals Joint Aids Programme (MJAP)

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  • Achan Beattrice, BDS, MMED., Makerere University College of Health Sciences

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  • Lodiongo Denis, BSc, Makerere University

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  • Guma Fred, BBLT, Makerere University

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  • Arinaitwe Eugene, BBLT, Msc Mol Biol., Makerere University

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  • Kiyimba Anthony, BBLT, Makerere University

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  • Oyom Christopher, BBLT, Makerere University

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  • Olia Alex, BBLT, Msc Mol Biol., Makerere University

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  • Metegeki Ezra, BBLT, Makerere University

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Download application form  PDF Format        MS Word Format
Curriculum for Applied and Diagnostic Molecular Biology/Immunology practicum
Lecture notes/presentations for 2010 practicum
Pictorial events for 2010 practicum