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The laboratories of the department of medical microbiology provide a vibrant research and training environment for both undergraduate and graduate students. It is these laboratories (Clinical Microbiology, Molecular Biology, Molecular Diagnostics, Immunology, Mycobacteriology and Mycology laboratories) that support students’ research and/or training. We serve health professionals, research scientists and students’ interests spanning from high school vacationists, undergraduates, Masters, and PhD candidates. Whether you are a student, health professional or high caliber Researcher (local or International), the department of Medical Microbiology warmly welcomes you to visit her research facilities for a friendly discussion.
The molecular biology laboratory and the clinical microbiology labs continue to be hubs for undergraduate industrial and research training in clinical microbiology and Molecular techniques. The laboratories have so far trained approx 400 undergraduate students from undergraduate programmes of Makerere University, Kyambogo University and Kampala International University. Likewise, the molecular biology laboratory has been a hub for undergraduate research training. The laboratory has trained approx 50 undergraduate students for their first degree undergraduate research projects.

Below is a summary of representative students and their research topics.


2004:

  • B-lactamase production among Escherichia coli isolate of community origin. By Katabazi Ashaba Fred, BBLT, Mak.

Supervisor: Florence Najjuka, MBChB, MMED, MSC.

2005:

  • Quantitative sputum bacillary response to short course chemotherapy in new and re-treated adults with pulmonary tuberculosis at JCRC. By Lukyamuzi George, BBLT, Mak.

Supervisor: Moses L. Joloba, PhD.

2006:

  • Comparison of various concentrations of carbolfuchsin in Zeihl-Neelsen for detection of acid-fast bacilli in sputum samples in Kampala district. By Ezati Nicholas, BBLT, Mak.

Supervisor: Moses L. Joloba, PhD.

  • Time to detection of Mycobacterium tuberculosis in Sputum Cultured on Lowenstein-Jensen Media: A case study of the National Tuberculosis and Leprosy Programme Unit, Ministry of Health. By Natukwatsa K. Johnson, BBLT, Mak.

Supervisor: Moses L. Joloba, PhD.

2008:

  • Evaluation of PCR for detection of Mycobacterium tuberculosis complex in sputum smear negative samples using chelex-100 as DNA extraction method. By Nakanjako Ritah, BBLT, Mak.

Supervisor: Benon B. Asiimwe, PhD & Moses L. Joloba, PhD.

  • Effect of cell density on the transformation efficiency of mycobacterium smegamtis with palsimd DNA. By Mboowa Gerald, BBLT, Mak.

Supervisor: David P. Kateete, BVM, MSC & Moses L. Joloba, PhD
.

  • Improvement of template DNA extraction and determination of optimum concentration of DNA for PCR detection detection of mycobacterium tuberculosis in a Ugandan laboratory setting. By Ssenyonjo Andrew, BBLT, Mak.

Supervisor: David P. Kateete, BVM, MSC. & Moses L. Joloba, PhD.

  • Direct PCR detection of Mycobacterium tuberculosis complex in cerebralspinal fluid (CSF) of patients with suspected meningeal tuberculosis in Mulago hospital, Kampala. By Okeng Alfred, BBLT, Mak.

Supervisor: Bwanga Freddie, MbChB, MMED.

  • Detection of the intercellular adhesion D (icaD) gene and biofilm production in a collection of Staphylococcus epidermidis isolates. By Okee Moses, BBLT, Mak.

Supervisor: David P. Kateete, BVM, MSC & Moses L. Joloba, PhD.

2009

  • Comparison of the specificity and sensitivity of sheep and human plasma in detecting coagulase production by Staphylococcus aureus clinical isolates.  By Ndung’u Kimani Cyrus, BBLT, Mak.

Supervisors: Florence Najjuka, MBChB, MMED, MSC, & David P. Kateete, BVM, MSC.

  • Steven Tukwasibwe, BBLT, Mak.

Supervisors: David P. Kateete, BVM, MSC., Moses L. Joloba, PhD & Matovu Enoch, PhD

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2000

Joloba M L; Bajaksouzian S; Jacobs M R. Evaluation of Etest for susceptibility testing of Mycobacterium tuberculosis. Journal of clinical microbiology 2000;38(10):3834-6.
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Joloba M L; Johnson J L; Namale A; Morrissey A; Assegghai A E; Mugerwa R D; Ellner J J; Eisenach K D. Quantitative sputum bacillary load during rifampin-containing short course chemotherapy in human immunodeficiency virus-infected and non-infected adults with pulmonary tuberculosis.
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Wallis R S; Perkins M D; Phillips M; Joloba M; Namale A; Johnson J L; Whalen C C; Teixeira L; Demchuk B; Dietze R; Mugerwa R D; Eisenach K; Ellner J J. Predicting the outcome of therapy for pulmonary tuberculosis.
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Joloba M L; Whalen C C; Cave D M; Eisenach K D; Johnson J L; Okwera A; Morrissey A; Bajaksouzian S; Feagin J; Mugerwa R; Ellner J; Jacobs M R. Determination of drug susceptibility and DNA fingerprint patterns of clinical isolates of Mycobacterium tuberculosis from Kampala, Uganda.
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1999
Wallis R S; Patil S; Cheon S H; Edmonds K; Phillips M; Perkins M D; Joloba M; Namale A; Johnson J L; Teixeira L; Dietze R; Siddiqi S; Mugerwa R D; Eisenach K; Ellner J J. Drug tolerance in Mycobacterium tuberculosis.
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Dranzoa C.; Ocaido M.; Katete P., 1999. The ecto-, gastro-intestinal and haemo-parasites of live pigeons (Columba livia) in Kampala, Uganda. Avian Pathology, Vol. 28(2), , pp. 119-124(6).
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Demissie A; Ravn P; Olobo J; Doherty T M; Eguale T; Geletu M; Hailu W; Andersen P; Britton S. T-cell recognition of Mycobacterium tuberculosis culture filtrate fractions in tuberculosis patients and their household contacts.
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Ravn P; Demissie A; Eguale T; Wondwosson H; Lein D; Amoudy H A; Mustafa A S; Jensen A K; Holm A; Rosenkrands I; Oftung F; Olobo J; von Reyn F; Andersen P. Human T cell responses to the ESAT-6 antigen from Mycobacterium tuberculosis.
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1998
Ssali F N; Kamya M R; Wabwire-Mangen F; Kasasa S; Joloba M; Williams D; Mugerwa R D; Ellner J J; Johnson J L. A prospective study of community-acquired bloodstream infections among febrile adults admitted to Mulago Hospital in Kampala, Uganda.
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Wallis R S; Perkins M; Phillips M; Joloba M; Demchuk B; Namale A; Johnson J L; Williams D; Wolski K; Teixeira L; Dietze R; Mugerwa R D; Eisenach K; Ellner J J. Induction of the antigen 85 complex of Mycobacterium tuberculosis in sputum: a determinant of outcome in pulmonary tuberculosis treatment.
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1995
Ozwara HS, Olobo JO, Irungu LW. Evaluation of immune associated cells in lesions of L. major infected vervet monkeys (Cercopithecus aethiops).  Afr J Health Sci. 1995 Aug;2(3):349-353.
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